<html>
<head></head>
<body>
<script type="text/javascript">
function changeText(e) {
    if(e.textContent == "Hello")
        e.textContent = "Goodbye cruel";
    else
        e.textContent = "Hello";
    }
</script>
<div>Line 1</div>
<div><span onclick="changeText(this)">Hello</span> world!</div>
<div>Line 3</div>
</body>
</html>