diff --git a/src/cthulhu/cthulhu.py b/src/cthulhu/cthulhu.py
index 997fb12..e22e693 100644
--- a/src/cthulhu/cthulhu.py
+++ b/src/cthulhu/cthulhu.py
@@ -638,6 +638,9 @@ def loadUserSettings(script=None, inputEvent=None, skipReloadMessage=False):
     _scriptManager.activate()
     _eventManager.activate()
 
+    cthulhuApp.getSignalManager().emitSignal('load-setting-begin')
+    cthulhuApp.getPluginSystemManager().register_plugin_keybindings_with_active_script()
+
     cthulhuApp.getSignalManager().emitSignal('load-setting-completed')
 
     debug.printMessage(debug.LEVEL_INFO, 'CTHULHU: User Settings Loaded', True)
diff --git a/src/cthulhu/plugin_system_manager.py b/src/cthulhu/plugin_system_manager.py
index 80fe9c5..a0f756e 100644
--- a/src/cthulhu/plugin_system_manager.py
+++ b/src/cthulhu/plugin_system_manager.py
@@ -156,6 +156,34 @@ class PluginSystemManager:
             import traceback
             logger.error(traceback.format_exc())
 
+    def register_plugin_keybindings_with_active_script(self):
+        """Register all plugin keybindings with the active script."""
+
+        if not PLUGGY_AVAILABLE:
+            return
+
+        from . import cthulhu_state
+        if not cthulhu_state.activeScript:
+            logger.warning("No active script available to register plugin keybindings")
+            return
+
+        active_script = cthulhu_state.activeScript
+        logger.info(f"Registering plugin keybindings with active script: {active_script}")
+
+        for pluginInfo in self._plugins.values():
+            if not pluginInfo.loaded or not pluginInfo.instance:
+                continue
+
+            plugin = pluginInfo.instance
+            if not hasattr(plugin, 'get_bindings') or not plugin.get_bindings():
+                continue
+
+            logger.info(f"Registering keybindings for plugin: {plugin.name}")
+            bindings = plugin.get_bindings()
+            for binding in bindings.keyBindings:
+                logger.info(f"Adding binding: {binding.keysymstring} with modifiers {binding.modifiers}")
+                active_script.getKeyBindings().add(binding)
+
     def _on_settings_changed(self):
         """Re-register all plugin keybindings when settings change."""
         if not hasattr(self, '_plugin_global_bindings'):
diff --git a/src/cthulhu/script_manager.py b/src/cthulhu/script_manager.py
index c55fb23..0f184ef 100644
--- a/src/cthulhu/script_manager.py
+++ b/src/cthulhu/script_manager.py
@@ -319,6 +319,14 @@ class ScriptManager:
 
         newScript.activate()
         tokens = ["SCRIPT MANAGER: Setting active script to", newScript, "reason:", reason]
+    self._activeScript = newScript
+
+    # Register plugin keybindings with the new active script
+    from . import cthulhu
+    plugin_manager = cthulhu.getPluginSystemManager()
+    if plugin_manager:
+        plugin_manager.register_plugin_keybindings_with_active_script()
+
         debug.printTokens(debug.LEVEL_INFO, tokens, True)
 
     def _getScriptForAppReplicant(self, app):